Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ AY 9944 dihydrochloride
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CAS: 366-93-8 Molecular Formula: C22H30Cl4N2
| CAS | 366-93-8 |
|---|---|
| Molecular Formula | C22H30Cl4N2 |
Tocris Bioscience™ AZ Dyrk1B 33
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Potent and selective Dyrk1B kinase inhibitor
Tocris Bioscience™ Chaetocin
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CAS: 28097-03-2 Molecular Formula: C30H28N6O6S4
| CAS | 28097-03-2 |
|---|---|
| Molecular Formula | C30H28N6O6S4 |
Tocris Bioscience™ DBM 1285 dihydrochloride
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p38 MAPK inhibitor; anti-inflammatory
| Inhibitors | DBM 1285 dihydrochloride |
|---|---|
| Product Type | DBM 1285 dihydrochloride |
| Molecular Weight (g/mol) | 468.42 |
| Purity | >98% |
Tocris Bioscience™ (R)-DRF053 dihydrochloride
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Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
| Inhibitors | (R)-DRF053 dihydrochloride |
|---|---|
| Product Type | (R)-DRF053 dihydrochloride |
| Molecular Weight (g/mol) | 490.43 |
| Purity | >98% |
Tocris Bioscience™ (RS)-CPP
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CAS: 100828-16-8 Molecular Formula: C8H17N2O5P
| CAS | 100828-16-8 |
|---|---|
| Molecular Formula | C8H17N2O5P |
Tocris Bioscience™ iCRT 14
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CAS: 677331-12-3 Molecular Formula: C21H17N3O2S
| CAS | 677331-12-3 |
|---|---|
| Molecular Formula | C21H17N3O2S |
Tocris Bioscience™ GW 4064
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CAS: 278779-30-9 Molecular Formula: C28H22Cl3NO4
| CAS | 278779-30-9 |
|---|---|
| Molecular Formula | C28H22Cl3NO4 |
Tocris Bioscience™ K 03861
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Potent CDK2 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 853299-07-7 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H26F3N7O2 |
Tocris Bioscience™ A 438079 hydrochloride
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CAS: 899431-18-6 Molecular Formula: C13H10Cl3N5
| CAS | 899431-18-6 |
|---|---|
| Molecular Formula | C13H10Cl3N5 |
Tocris Bioscience™ AP 24534
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CAS: 943319-70-8 Molecular Formula: C29H27F3N6O
| CAS | 943319-70-8 |
|---|---|
| Molecular Formula | C29H27F3N6O |
Tocris Bioscience™ 20(S)-Hydroxycholesterol
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CAS: 516-72-3 Molecular Formula: C27H46O2
| CAS | 516-72-3 |
|---|---|
| Molecular Formula | C27H46O2 |
Tocris Bioscience™ 4-Methylhistamine dihydrochloride
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Selective, high affinity H4 agonist
| CAS | 36376-47-3 |
|---|---|
| Solubility | Soluble to 50mM in water |
| Chemical Name or Material | 5-(2-Aminoethyl)-4-methylimidazole dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C6H11N3.2HCl |
| Formula Weight | Observed MW: 198.09 |
Tocris Bioscience™ OSU 03012
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PDPK1 (PDK1) inhibitor; inhibits Akt signaling
| Target | PDK-1 Inhibitors |
|---|---|
| CAS | 742112-33-0 |
| Purity | >98% |
| Chemical Name or Material | 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H19F3N4O |
| Formula Weight | 460.45 |
Tocris Bioscience™ Bexarotene
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Potent and selective RXR agonist
| Target | Retinoid X Receptor Agonists |
|---|---|
| CAS | 153559-49-0 |
| Purity | >99% |
| Chemical Name or Material | 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid |
| Recommended Storage | Store at 4°C |
| Synonym | LGD 1069 |
| Molecular Formula | C24H28O2 |
| Formula Weight | 348.48 |